Journal of Community Health Provision

Biological Effects of Ajwa Dates for Pre-Conception Women

2026-07-24T14:17:11+00:00

Ajwa dates are functional foods that contain bioactive compounds and essential nutrients with potential benefits for women’s reproductive health, particularly during the preconception period. This study aimed to examine the biological effects of Ajwa dates on preconception women, focusing on their nutritional benefits, antioxidant and anti-inflammatory activities, hormonal regulation, ovarian function, and pregnancy readiness. This study used a narrative literature review design based on secondary data obtained from scientific publications published between 2021 and 2026. Data were collected from accredited national journals, reputable international journals, scientific proceedings, and databases such as PubMed, Google Scholar, ScienceDirect, DOAJ, and local open-access journal portals. The selected articles were analyzed using narrative synthesis through thematic organization, comparison between studies, conceptual synthesis, and conclusion drawing. The findings indicate that Ajwa dates contain phenolics, flavonoids, vitamins, minerals, polysaccharides, dietary fiber, and other bioactive compounds that contribute to antioxidant and anti-inflammatory activities. Several studies show that Ajwa dates may help reduce oxidative stress, improve antioxidant defense, modulate inflammatory responses, support hormonal balance, and protect ovarian function, including slowing the decline of Anti-Müllerian Hormone and influencing ovarian follicle characteristics. Ajwa dates also provide nutritional support that may improve women’s physiological readiness before pregnancy.

Platelet Analysis in Pediatric Patients with Acute Gastroenteritis at RSIA Sitti Khadijah 1 Makassar

2026-04-21T10:41:16+00:00

Acute gastroenteritis (AGE) is an inflammation of the stomach and intestines with symptoms of diarrhea, nausea and vomiting, experienced for less than 14 days, with a fairly high prevalence worldwide. One of the laboratory tests carried out is routine blood, including platelet count. When inflammation occurs, platelet production will increase in response from the immune system. To analyze platelets in acute gastroenteritis (AGE) sufferers. The methods of the research is descriptive retrospective using medical record data of acute gastroenteritis (AGE) sufferers. Results showed that the age distribution of samples was grouped into three groups, namely < 2 years, 3-5 years, and 6-10 years with the main complaints of diarrhea, vomiting, and diarrhea accompanied by vomiting. The platelet count of acute gastroenteritis (AGE) sufferers is more normal, but there is an increase in platelet count in the < 2 years age group with complaints of diarrhea accompanied by vomiting. There is no relationship between platelet count and complaints of diarrhea, vomiting, and diarrhea accompanied by vomiting in acute gastroenteritis (AGE) sufferers.

Effectiveness of TikTok-Based Health Education in Improving Pregnant Women's Knowledge of Abortion Prevention: A Quasi-Experimental Study

2026-07-27T11:18:18+00:00

Pregnant women's knowledge regarding abortion prevention remains an important determinant in reducing the risk of maternal morbidity associated with abortion. The rapid growth of social media has created new opportunities to deliver health education through engaging and accessible platforms such as TikTok. This study aimed to analyze the effect of TikTok-based health education on pregnant women's knowledge regarding abortion prevention at Sultan Thaha Saifuddin Regional General Hospital, Tebo Regency. A quasi-experimental one-group pretest-posttest study was conducted at the hospital's Obstetric Clinic in February 2026. Thirty-five pregnant women were recruited using accidental sampling. Participants received standardized educational videos on abortion prevention delivered through TikTok. Knowledge was assessed using a structured questionnaire before and after the intervention. Data normality was evaluated using the Shapiro–Wilk test, and differences in knowledge scores were analyzed using the paired samples t-test with a significance level of α = 0.05. The mean knowledge score increased from 12.31 ± 2.45 before the intervention to 17.94 ± 1.61 after the intervention. The Shapiro–Wilk test confirmed that the data were normally distributed (p > 0.05). Paired samples t-test demonstrated a statistically significant improvement in knowledge, with a mean difference of 5.63 (95% CI: 4.91–6.34; p < 0.001). The intervention also showed a very large effect size (Cohen's d = 2.74). These findings indicate that TikTok-based health education is effective in improving pregnant women's knowledge regarding abortion prevention and may serve as an innovative educational strategy to strengthen health promotion within antenatal care services.

Serum Procalcitonin in Diabetes Mellitus with and Without Pulmonary Tuberculosis

2026-07-27T10:37:27+00:00

Diabetes mellitus (DM) is associated with immune dysfunction and increased susceptibility to pulmonary tuberculosis (TB). Procalcitonin (PCT) is widely used as a biomarker of bacterial infection, but its concentrations in patients with DM and pulmonary TB remain insufficiently characterized. To compare serum PCT concentrations between patients with DM with and without active pulmonary TB. This analytical cross-sectional study included 50 patients with DM recruited from two primary healthcare centers in Jambi, Indonesia, from March to June 2026. Participants comprised 34 patients without pulmonary TB and 16 with active pulmonary TB. Serum PCT was measured using fluorescence immunoassay. Non-normally distributed PCT concentrations were summarized using the median and interquartile range (IQR) and compared using the Mann–Whitney U test.PCT concentrations were within the normal reference range (<0.05 ng/mL) in 33/34 (97.1%) patients without pulmonary TB and 13/16 (81.3%) patients with active pulmonary TB. Because measurements at or below 0.05 ng/mL were retained as thresholded values, the median (IQR) was ≤0.05 (≤0.05–≤0.05) ng/mL in both groups. No statistically significant between-group difference was identified (U = 230.000, Z = −1.857, p = 0.063). Serum PCT concentrations did not differ significantly between patients with DM with and without active pulmonary TB. Larger studies with standardized TB confirmation, assessment of treatment status and relevant confounders, and diagnostic-accuracy analyses are warranted.

Dates and Honey in Nutritional Status in Pregnant Women: Systematic Review

2026-07-15T10:19:20+00:00

Optimal nutritional status during pregnancy is an important factor in supporting maternal health and fetal growth. In Islam, Thibbun Nabawi (Prophetic medicine) includes various natural food ingredients such as honey and dates, which are believed to have health benefits. The objective the research to analyze scientific evidence regarding the effect of dates and honey on the nutritional status of pregnant women based on the results of recent research. Methods: This study used a systematic review method with reference to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Literature was obtained from PubMed, Scopus, ScienceDirect, SpringerLink, Cochrane Library, and Google Scholar databases in the period January–May 2026. Articles that met the inclusion criteria were observational studies, randomized controlled trials, systematic reviews, and meta-analyses published between 2015–2025. Data were extracted and analyzed using narrative synthesis. Results showed that Thibbun Nabawi components have the potential to improve the nutritional status of pregnant women. Date consumption is associated with increased hemoglobin levels, improved energy status, and better preparation for childbirth. Honey has a positive effect on increasing energy intake and antioxidant status, and helps reduce fatigue during pregnancy. Conclusion: Dates and honey have the potential to benefit the nutritional status of pregnant women by increasing energy intake and micronutrients, antioxidant activity, and supporting maternal health. However, more robust clinical studies are needed to determine the effectiveness, optimal dosage, and safety of using various components of Thibbun Nabawi during pregnancy.

Association of Lipid Profile, Glycated Hemoglobin (HbA1c), and Hypertension History with Coronary Artery Disease among Adult Patients: A Cross-Sectional Study

2026-07-28T11:03:43+00:00

Coronary artery disease (CAD) remains a major cause of cardiovascular morbidity and mortality worldwide. This study aimed to examine the association of lipid profile, glycated hemoglobin (HbA1c), and hypertension history with CAD among adult patients. A cross-sectional analytical study was conducted among 40 adult patients undergoing cardiovascular evaluation at Abdul Manap Regional General Hospital, Jambi, Indonesia, including 20 patients with CAD and 20 participants without CAD. Demographic characteristics, lipid profile, HbA1c levels, hypertension history, diabetes mellitus status, smoking status, and body mass index were obtained from medical records and laboratory examinations. Bivariate analyses used independent t-tests, Mann–Whitney U tests, Chi-square tests, or Fisher’s exact tests, followed by multivariable binary logistic regression. Participants with CAD were older and had higher BMI, total cholesterol, LDL cholesterol, triglycerides, and HbA1c levels, but lower HDL cholesterol. After adjustment, age (aOR = 1.13; p = 0.039), BMI (aOR = 1.75; p = 0.023), hypertension history (aOR = 13.71; p = 0.026), diabetes mellitus (aOR = 7.94; p = 0.044), LDL cholesterol ≥130 mg/dL (aOR = 10.49; p = 0.018), and HbA1c ≥6.5% (aOR = 9.10; p = 0.018) were independently associated with CAD. Older age, higher BMI, hypertension, diabetes, elevated LDL cholesterol, and poor glycemic control were independently associated with CAD.

Development and Validation of a Specific PCR Primer for the Detection of the Meca Gene in MRSA

2026-05-13T14:06:47+00:00

Methicillin-Resistant Staphylococcus aureus (MRSA) is a major pathogen responsible for nosocomial infections with high prevalence in Indonesia. The mecA gene encodes beta-lactam antibiotic resistance, making its specific molecular detection crucial for rapid diagnosis and infection control. This study aimed to develop and validate specific PCR primers for detecting the mecA gene in MRSA as a marker of antibiotic resistance. Laboratory experimental research was conducted at the UPH Advanced Biology Laboratory in November 2025 using certified pure MRSA isolates. DNA extraction was performed with the QIAamp DNA Mini Kit and quantified using a spectrophotometer. Primer design was carried out in silico using NCBI PrimerBLAST and BioEdit, followed by conventional PCR optimization with varying annealing temperatures. Amplification results were validated through agarose gel electrophoresis, with qualitative assessment based on DNA band intensity and sharpness. The mecA primer successfully amplified an 818-bp fragment at an optimal annealing temperature of 55.5°C, producing a single, sharp band without smearing. The negative control (S. aureus) showed no amplification, confirming primer specificity. Despite low DNA concentrations (4.5–7.6 ng/μL), amplification was consistently successful, indicating that this method is capable of reliably detecting the target gene at low DNA levels. This validated method provides an accurate molecular diagnostic tool for rapid identification of resistant pathogens. It supports epidemiological surveillance, nosocomial infection control, and early detection programs within the Indonesian healthcare system. By enabling precise detection of mecA-mediated resistance, the approach strengthens laboratory capacity for monitoring MRSA and contributes to improved public health strategies.

Educational Pocket Book on Medication Compliance and Tuberculosis Transmission Prevention in Patients at Simpang Lima Gumul Regional Hospital, Kediri

2026-05-25T09:12:50+00:00

Tuberculosis (TB) remains a global health problem with a high number of cases and low patient adherence to treatment. Health education is needed to improve treatment adherence and prevent TB transmission. This study aims to analyze the implementation of a pocketbook education on treatment adherence and transmission prevention in TB patients at Simpang Lima Gumul Regional Hospital, Kediri. This study used a qualitative descriptive approach with a SWOT analysis method. The study population consisted of TB patients and health workers at Simpang Lima Gumul Regional Hospital, Kediri, with samples selected using a purposive sampling technique. The research instruments included interview guidelines, observation sheets, documentation, and pre- and post-tests. Data analysis was carried out through data reduction, data presentation, conclusion drawing, and SWOT analysis. The results showed that health education using a pocketbook media increased the level of patient understanding from 20%. The results showed that the level of patient knowledge and adherence was in the good category with an average of 77.5%. Approximately 75–80% of respondents showed an increase in understanding after being provided with education. The SWOT analysis showed that the SO strategy was the main approach through optimization of educational media, support for national programs, and family involvement. The conclusion of this study is that education through pocket books is effective in increasing patient knowledge regarding treatment compliance and preventing TB transmission, thus supporting the success of TB treatment and control in hospitals.

Literature Review: The Effect of Fermented Food Consumption (Kombucha, Kimchi, Yogurt) on Antioxidant Status and Gastric Tract Health

2026-07-27T10:55:47+00:00

Gut health and redox balance play an important role in the prevention of various chronic diseases associated with oxidative stress and gut microbiota dysbiosis. The consumption of fermented foods such as kombucha, kimchi, and yogurt has gained increasing attention due to their potential benefits in improving antioxidant status and gastrointestinal health. This study aimed to review the effects of kombucha, kimchi, and yogurt consumption on antioxidant status and gut health. This study was conducted as a literature review using a systematic narrative review approach. Article searches were performed through PubMed/MEDLINE, ScienceDirect, the Directory of Open Access Journals (DOAJ), and Google Scholar. Included articles were published within the last ten years, available in full text, and relevant to the research topic. Article selection involved duplicate removal, title and abstract screening, and full-text assessment based on predefined inclusion and exclusion criteria. The synthesis results indicate that fermented food consumption is consistently associated with increased antioxidant capacity, reduced oxidative stress markers, and improved gut health through modulation of gut microbiota and increased production of fermentation-derived metabolites. Kombucha, kimchi, and yogurt exhibit complementary benefits in supporting microbiota balance and antioxidant status. In conclusion, the consumption of fermented foods has the potential to serve as a safe functional dietary intervention to support gut health and antioxidant balance.

The Effect of Health Education on Improving Knowledge of Oxytocin Massage Among Breastfeeding Mothers at Puskesmas Godean II, Sleman

2026-08-10T10:07:26+00:00

Breastfeeding mothers' knowledge of oxytocin massage remains relatively low. Limited knowledge may prevent mothers from understanding the benefits and proper techniques of oxytocin massage to facilitate breast milk secretion. One approach that can be implemented to improve maternal knowledge is health education. This study aimed to determine the effect of health education on improving breastfeeding mothers' knowledge of oxytocin massage at Godean II Public Health Center, Sleman. This quantitative study employed a pre-experimental one-group pretest-posttest design. The study population consisted of 43 breastfeeding mothers, with a sample of 30 respondents selected using purposive sampling. The research instrument was a knowledge questionnaire on oxytocin massage consisting of 15 questions. Data were analyzed using the Paired Samples t-test. The results showed that before the health education intervention, respondents' knowledge scores ranged from 7 to 11, whereas after the intervention, the scores increased to 13–15. The results of the bivariate analysis using the Paired Samples t-test before and after the health education intervention yielded a P-value of <0.001 (p < 0.05). These findings indicate a significant improvement in knowledge following the health education intervention.

Salvaging the Right Middle Finger with an Abdominal Flap Following Degloving Injury and Traumatic Amputation at the DIP Joint: A Case Report

2026-07-27T10:52:56+00:00

Degloving injury represents one of the most challenging forms of hand trauma. Various salvage strategies have been described in the literature, including primary reattachment of avulsed skin, reconstruction using free flaps and full-thickness skin grafts (FTSG), as well as replantation and microvascular revascularization, with the choice of technique depending on the specific characteristics and severity of the injury. However, no single reconstructive method has been universally established as the gold standard; therefore, treatment should be individualized with the primary aim of preserving tissue viability and optimizing functional outcomes. A 39-year-old man was referred from a type B hospital in Parepare, presenting with an open injury of the right middle finger following a ring avulsion injury. The injury occurred when the ring worn on the patient’s middle finger became caught on the metal handle of a pickup truck while he was stepping out of the vehicle, resulting in avulsion of the skin and subcutaneous tissue of the affected digit. At the time of injury, the patient was unaware of the detached soft tissue, and the avulsed tissue was not retrieved or brought to the hospital. The patient initially presented to a type C hospital for primary management, was subsequently referred to a type B hospital, and was finally transferred to Makassar for definitive treatment. Skin loss due to traumatic amputation. The patient underwent abdominal flap reconstruction. The results show that the salvage procedure successfully preserved the right middle finger up to the level of the middle phalanx, maintaining digit length despite residual postoperative stiffness. Initial management and available healthcare facilities play a crucial role in determining the feasibility of replantation as well as the selection of appropriate salvage reconstructive options for degloving injuries.

Occupational Safety and Health Risk Assessment Among Office Employees at the Environmental Agency of Karawang Regency

2026-07-27T11:03:24+00:00

Office work environments are exposed to various occupational hazards that may affect occupational safety and health (OSH). This study aimed to identify workplace hazards, assess occupational risks using the Hazard Identification, Risk Assessment, and Determining Control (HIRADC) method, and analyze factors associated with OSH risk among office employees at the Environmental Agency of Karawang Regency, Indonesia. A quantitative cross-sectional study was conducted involving 63 employees selected through total sampling. Data were collected using HIRADC observations and structured questionnaires and analyzed using univariate analysis, Chi-square test, and binary logistic regression. The results identified 20 workplace hazards, consisting of 1 low-risk (5.0%), 14 medium-risk (70.0%), and 5 high-risk (25.0%) hazards. Bivariate analysis revealed that physical factors (p<0.001) and safety factors (p=0.001) were significantly associated with OSH risk levels. Multivariate analysis indicated that safety factors were the strongest predictor of OSH risk (OR=6.594; p=0.011), followed by physical factors (OR=4.786; p=0.029). Periodic implementation of HIRADC and strengthening of the Occupational Safety and Health Management System (OSHMS) based on ISO 45001:2018 are recommended to reduce occupational risks and improve workplace safety in office environments.

The Role of Thiazide Diuretics in Hypertension with Chronic Kidney Disease: Benefits and Risks

2026-07-27T10:36:05+00:00

Hypertension is a common complication of chronic kidney disease (CKD) and contributes to renal disease progression and cardiovascular risk. Although the effectiveness of thiazide diuretics in advanced CKD has been questioned, recent evidence indicates that thiazide and thiazide-like diuretics remain useful for blood pressure control. This literature review aimed to evaluate the role, benefits, and potential risks of thiazide diuretics in managing hypertension among patients with CKD. A narrative literature review was conducted using national and international journals and clinical practice guidelines published between 2021 and 2026. A total of 806 articles were identified, and 11 studies met the predefined inclusion and exclusion criteria for qualitative analysis. The findings demonstrated that thiazide and thiazide-like diuretics effectively reduced blood pressure in patients with CKD, including those with advanced disease and resistant hypertension. Chlorthalidone significantly reduced systolic blood pressure and albuminuria, indicating potential renoprotective benefits. Combination therapy with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers provided better blood pressure control than monotherapy. However, adverse effects included hypokalemia, hyponatremia, hyperuricemia, hypotension, and transient increases in serum creatinine. Thiazide diuretics remain valuable for hypertension management in CKD, but treatment should be individualized and accompanied by regular monitoring of renal function and electrolytes. Lifestyle modification should complement pharmacological therapy to optimize outcomes.

Overview of Cataract Risk Factors in Productive Age Patients: Literature Review

2026-09-10T01:57:15+00:00

Cataract is a leading cause of visual impairment and blindness that occurs not only in the elderly but also among the productive-age population. Various risk factors are thought to contribute to the development of cataracts in this age group; therefore, a comprehensive understanding of these factors is needed. This study aimed to analyze the risk factors for cataracts in productive-age patients based on recent literature. This study employed a narrative review method by examining various scientific articles obtained from the PubMed, ScienceDirect, and Google Scholar databases. The literature search was conducted using keywords relevant to the research topic. The main risk factors for cataracts in productive-age patients include ultraviolet radiation exposure, diabetes mellitus, hypertension, smoking habits, outdoor occupations, nutritional status, and socioeconomic conditions. In addition, family history, sex, and refractive errors also contribute to an increased risk of cataract development. The occurrence of cataracts in productive-age patients is multifactorial; therefore, promotive and preventive efforts through the control of modifiable risk factors are needed to reduce the incidence of early-onset cataracts.

Congenital Hypothyroidism in a 7-Month-Old Infant with Developmental Delay and Stunting

2026-09-08T07:25:07+00:00

Congenital hypothyroidism is a preventable cause of growth, developmental, and intellectual disorders when diagnosis and treatment are initiated early. However, clinical manifestations may be subtle during the early stages, resulting in delayed diagnosis when neonatal screening is not performed. This case report describes the clinical presentation, diagnosis, and management of congenital hypothyroidism diagnosed after the neonatal period. A 7-month-old female presented with developmental delay, poor weight gain, constipation, and reduced responsiveness to her environment. Physical examination revealed macroglossia and growth and developmental delays. Anthropometric measurements showed a weight of 5 kg, height of 60 cm, weight-for-age of -2.95, height-for-age of -2.61, and weight-for-height of -1.66. Laboratory evaluation revealed a free thyroxine (FT4) level of 5.15 pmol/L and thyroid-stimulating hormone (TSH) >100,000 µIU/mL, confirming congenital hypothyroidism with stunting. Treatment consisted of levothyroxine at an initial dose of 10 µg/kg/day, nutritional intervention, and physical therapy. After two months, FT4 increased to 11.06 pmol/L and TSH decreased to 12.906 µIU/mL, accompanied by increased activity, weight gain, and developmental improvement. This case emphasizes the importance of neonatal screening, early recognition of developmental abnormalities, and prompt treatment to minimize the adverse consequences of congenital hypothyroidism.

Literature Review: Fermented Dairy Food Effect on Cardiovascular Biomarker

2026-07-27T10:34:39+00:00

Fermented dairy products are functional foods rich in probiotics, bioactive peptides, and nutrients that may provide cardiovascular health benefits. However, evidence regarding their effects on cardiovascular biomarkers remains inconsistent. This study reviewed scientific evidence on the effects of fermented dairy products on cardiovascular biomarkers. A literature review was conducted using national and international publications published between 2020 and 2026. Literature searches were performed through PubMed, Google Scholar, ScienceDirect, SpringerLink, ProQuest, and ResearchGate. Eligible studies were analyzed narratively by summarizing, synthesizing, comparing, contrasting, and critically evaluating their findings. A total of 17 scientific articles met the inclusion criteria and were analyzed. The findings indicate that fermented dairy products, particularly yogurt, kefir, and cheese, may improve cardiovascular biomarkers by reducing total cholesterol and low-density lipoprotein (LDL) levels, increasing high-density lipoprotein (HDL) levels, and decreasing inflammatory biomarkers such as C-reactive protein (CRP). They may also improve glycemic control, modulate gut microbiota by increasing short-chain fatty acid (SCFA)-producing bacteria, and reduce cardiovascular disease risk. However, effects vary according to product type, probiotic composition, dosage, intervention duration, and participant characteristics. Overall, fermented dairy products show potential to support cardiovascular health through improvements in lipid profiles, inflammation, gut microbiota, and glycemic control. Further large-scale clinical trials and well-designed interventions are needed to establish causal relationships and determine optimal consumption strategies.

LC–MS/MS Profiling the Dichloromethane Fraction of Endophytic Fusarium proliferatum CSBT2 Isolated from Curcuma sumatrana Miq

2026-08-19T08:37:03+00:00

Endophytic fungi are recognized as a rich source of structurally diverse secondary metabolites. However, the metabolite composition of endophytic fungi associated with the endemic medicinal plant Curcuma sumatrana Miq. remains largely unexplored. This study aimed to profile the major metabolites present in the dichloromethane (DCM) fraction of Fusarium proliferatum CSBT2 isolated from C. sumatrana. The fungus was cultivated in Potato Dextrose Broth (PDB) prepared according to the ATCC Medium 336 formulation, followed by extraction with ethyl acetate and fractionation to obtain the DCM fraction. Metabolite profiling was performed using LC–MS/MS, and compound annotation was based on accurate mass, fragmentation patterns, and database comparison. Several major metabolites were tentatively identified, including dehydrofusaric acid, fusaric acid, beauvericin, rhynchophylline, and solanidine. Most identified metabolites have previously been reported from Fusarium species, whereas the detection of solanidine may be associated with the potato-based cultivation medium. This study provides the first LC–MS/MS profile of the DCM fraction of F. proliferatum CSBT2 isolated from C. sumatrana. These findings expand the current knowledge of metabolites produced by Indonesian endophytic fungi and provide a basis for future isolation and biological evaluation of the detected compounds.