The Relationship Between Cholesterol Levels and Blood Pressure in the Elderly

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Published: Sep 3, 2025
DOI: https://doi.org/10.55885/jchp.v5i2.652
Keywords:
Hypertension, Hypercholesterolemia, Eldery, Blood pressure, Dyslipidemia

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Ardi Pramono
Department of Anesthesia and Intensive Therapy, University of Muhammadiyah Yogyakarta, Indonesia
Qoni Ihda Permata Sari
Medical Professional Education Study Program, Faculty of Medicine and Health Sciences, University of Muhammadiyah Yogyakarta/PKU Muhammadiyah Gamping Hospital, Yogyakarta, Indonesia

Abstract

Hypertension and hypercholesterolemia are two common comorbidities in the elderly and contribute greatly to the increased risk of cardiovascular disease. The two are often found together, but local data on the direct relationship between the two in the elderly population is limited. The purpose of this study is to find out whether there is a relationship between total cholesterol levels and blood pressure in the elderly. This study uses an observational analytical design with a cross-sectional approach. The subjects of the study were 16 elderly members of the posyandu in Balecatur, Sleman, who met the inclusion criteria. Blood pressure was measured using a sphygmomanometer, and total cholesterol levels were measured using a point-of-care device. Data were analyzed using the chi-square test to determine the relationship between cholesterol levels and hypertension. Of the total 16 respondents, as many as 13 people (81.25%) had blood pressure in the hypertension category, and 13 people (81.25%) had total cholesterol levels ≥200 mg/dL. The results of the statistical test showed that there was a significant relationship between cholesterol levels and blood pressure, with a value of p = 0.018 (p < 0.05). From this study, it was found that there was a significant relationship between cholesterol levels and blood pressure in the elderly. These findings confirm the importance of integrated screening for dyslipidemia and hypertension in promotive and preventive programs in the elderly population.

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How to Cite
Pramono, A., & Sari, Q. I. P. (2025). The Relationship Between Cholesterol Levels and Blood Pressure in the Elderly . Journal of Community Health Provision, 5(2), 99-104. https://doi.org/10.55885/jchp.v5i2.652
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Vol. 5 No. 2 (2025): Journal of Community Health Provision
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Articles
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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

References

Brown, N. J. (2008). Aldosterone and vascular inflammation. Hypertension, 51(2), 161-167. https://doi.org/10.1161/HYPERTENSIONAHA.107.095489

Chia, C. W., Egan, J. M., & Ferrucci, L. (2018). Age-related changes in glucose metabolism, hyperglycemia, and cardiovascular risk. Circulation research, 123(7), 886-904. https://doi.org/10.1161/CIRCRESAHA.118.312806

Ciumărnean, L., Milaciu, M. V., Negrean, V., Orășan, O. H., Vesa, S. C., Sălăgean, O., ... & Vlaicu, S. I. (2021). Cardiovascular risk factors and physical activity for the prevention of cardiovascular diseases in the elderly. International Journal of Environmental Research and Public Health, 19(1), 207. https://doi.org/10.3390/ijerph19010207

Dąbrowska, E., & Narkiewicz, K. (2023). Hypertension and dyslipidemia: the two partners in endothelium-related crime. Current Atherosclerosis Reports, 25(9), 605-612. https://doi.org/10.1007/s11883-023-01132-z

Dai, Y., Teng, D., Zhang, C., Wang, H., Lai, Y., Ding, S., ... & Li, Y. (2024). Priorities in tackling noncommunicable diseases among the population aged 60 years and older in China, 1990–2021: a population-based study. Ageing research reviews, 102, 102574. https://doi.org/10.1016/j.arr.2024.102574

Egan, B. M., Mattix-Kramer, H. J., Basile, J. N., & Sutherland, S. E. (2024). Managing hypertension in older adults. Current hypertension reports, 26(4), 157-167. https://doi.org/10.1007/s11906-023-01289-7

Gaggini, M., Gorini, F., & Vassalle, C. (2022). Lipids in atherosclerosis: pathophysiology and the role of calculated lipid indices in assessing cardiovascular risk in patients with hyperlipidemia. International journal of molecular sciences, 24(1), 75. https://doi.org/10.3390/ijms24010075

Hussain, M. A., Mamun, A. A., Reid, C., & Huxley, R. R. (2016). Prevalence, awareness, treatment and control of hypertension in Indonesian adults aged≥ 40 years: findings from the Indonesia Family Life Survey (IFLS). PloS one, 11(8), e0160922. https://doi.org/10.1371/journal.pone.0160922

John, S., & Schmieder, R. E. (2003). Potential mechanisms of impaired endothelial function in arterial hypertension and hypercholesterolemia. Current hypertension reports, 5(3), 199-207. https://doi.org/10.1007/s11906-003-0021-1

Lai, W., Chen, X., Wang, L., Wu, L., Li, X., & Zhou, B. (2025). Association between LDL/HDL ratio and hypertension in Chinese middle-aged and older adults: a cross-sectional and longitudinal analysis based on CHARLS LDL/HDL ration and hypertension. Frontiers in Endocrinology, 16, 1484318. https://doi.org/10.3389/fendo.2025.1484318

Maharani, R., Helda, H., & Amar, M. I. (2022). Risk Factors for Hypertension Incidence Among Women in Indonesia. Malaysian Journal of Public Health Medicine, 22(3), 310-318. https://doi.org/10.37268/mjphm/vol.22/no.3/art.1688

Muntner, P., Shimbo, D., Carey, R. M., Charleston, J. B., Gaillard, T., Misra, S., ... & Wright Jr, J. T. (2019). Measurement of blood pressure in humans: a scientific statement from the American Heart Association. Hypertension, 73(5), e35-e66. https://doi.org/10.1161/HYP.0000000000000087

Murakami, T. (2023). Atherosclerosis and arteriosclerosis. Hypertension Research, 46(7), 1810-1811. https://doi.org/10.1038/s41440-023-01284-0

Oliveros, E., Patel, H., Kyung, S., Fugar, S., Goldberg, A., Madan, N., & Williams, K. A. (2020). Hypertension in older adults: Assessment, management, and challenges. Clinical cardiology, 43(2), 99-107. https://doi.org/10.1002/clc.23303

Ranasinghe, P., Cooray, D. N., Jayawardena, R., & Katulanda, P. (2015). The influence of family history of hypertension on disease prevalence and associated metabolic risk factors among Sri Lankan adults. BMC public health, 15(1), 576. https://doi.org/10.1186/s12889-015-1927-7

Stokes, K. Y., Cooper, D., Tailor, A., & Granger, D. N. (2002). Hypercholesterolemia promotes inflammation and microvascular dysfunction: role of nitric oxide and superoxide. Free Radical Biology and Medicine, 33(8), 1026-1036. https://doi.org/10.1016/S0891-5849(02)01015-8

Thomas, F., Bean, K., Guize, L., Quentzel, S., Argyriadis, P., & Benetos, A. (2002). Combined effects of systolic blood pressure and serum cholesterol on cardiovascular mortality in young (< 55 years) men and women. European heart journal, 23(7), 528-535. https://doi.org/10.1053/euhj.2001.2888

Vekic, J., Stromsnes, K., Mazzalai, S., Zeljkovic, A., Rizzo, M., & Gambini, J. (2023). Oxidative stress, atherogenic dyslipidemia, and cardiovascular risk. Biomedicines, 11(11), 2897. https://doi.org/10.3390/biomedicines11112897

Wang, C., Du, Z., Ye, N., Shi, C., Liu, S., Geng, D., & Sun, Y. (2022). Hyperlipidemia and hypertension have synergistic interaction on ischemic stroke: insights from a general population survey in China. BMC cardiovascular disorders, 22(1), 47. https://doi.org/10.1186/s12872-022-02491-2

Zhang, Y., Vittinghoff, E., Pletcher, M. J., Allen, N. B., Zeki Al Hazzouri, A., Yaffe, K., ... & Moran, A. E. (2019). Associations of blood pressure and cholesterol levels during young adulthood with later cardiovascular events. Journal of the American college of cardiology, 74(3), 330-341. https://doi.org/10.1016/j.jacc.2019.03.529